Accumulation of Dobzhansky-Muller incompatibilities within a spatially structured population
Related Experiment Video
Updated: Sep 26, 2026

Conditions Affecting Social Space in Drosophila melanogaster
Published on: November 5, 2015
1National Center for Biotechnology Information, National Institutes of Health, 45 Center Drive, Bethesda, Maryland 20892-6510, USA. kondrashov@ncbi.nlm.nih.gov
Abstract:
A simple, deterministic analysis predicts that accumulation of Dobzhansky-Muller incompatibilities by a spatially structured population strongly depends on the number of negative interactions of an allele. If an allele can be incompatible with alleles at only one locus, incompatibilities accumulate linearly with time. In contrast, if an allele can participate in multiple pairwise incompatibilities with alleles at different loci, the expected number of incompatibilities eventually increases quadratically.
More Related Videos
Related Concept Videos
Understanding Species and Reproductive Barriers
Mutation, Gene Flow, and Genetic Drift
Hardy-Weinberg Principle
Hybrid Zones
Frequency-dependent Selection
Gene Flow

