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A novel type of fluorescent boronic acid that shows large fluorescence intensity changes upon binding with a
Wenqian Yang1, Jun Yan, Greg Springsteen
1Department of Chemistry, North Carolina State University, Raleigh, NC 27695-8204, USA.
Bioorganic & Medicinal Chemistry Letters
|March 20, 2003
Abstract:
In this paper we report 8-quinolineboronic acid as a novel type of fluorescent probe for carbohydrates. This boronic acid responds to the binding of a carbohydrate with over 40-fold increases in fluorescence intensity and shows optimal fluorescence change at physiological pH in aqueous solution.