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Novel alpha-amino-acid phenolic ester derivatives with intravenous anaesthetic activity
Andrew Cooke1, Alison Anderson, Jonathan Bennett
1Department of Medicinal Chemistry, Organon Laboratories Ltd., Newhouse, Scotland, ML1 5SH, UK. a.cooke@organon.co.uk
Bioorganic & Medicinal Chemistry Letters
|March 20, 2003
Abstract:
A novel series of alpha-amino-acid phenolic ester derivatives containing sulphide, sulphoxide, sulphone, ester and amide side chains were prepared and shown to display potent intravenous anaesthetic activity.