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Updated: Jul 30, 2026

Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores
Published on: August 19, 2013
Spectrophotometric and polarographic determination of enalapril and lisinopril using 2,4-dinitrofluorobenzene
O Abdel Razak1, S F Belal, M M Bedair
1Faculty of Pharmacy, Pharmaceutical Analytical Chemistry Department, University of Alexandria, P.O. Box El Mesallah, 21521, Alexandria, Egypt. pharmacy_alex@hotmail.com
Abstract:
The reaction of enalapril maleate and lisinopril with 2,4-dinitrofluorobenzene has been used to form colored products and polarographically active derivatives. The different experimental conditions have been optimized. The proposed methods have been validated and applied to the determination of both drugs in their commercial tablets. The results have been statistically compared with those obtained using the official HPLC methods.
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