Related Experiment Video
Updated: Jul 22, 2026

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging
Published on: April 11, 2025
Prognosis of brain stem lesion in children with head injury
Dieter Woischneck1, Susan Klein, Steffen Reissberg
1Klinik für Neurochirurgie, Otto-von-Guericke Universität, Leipziger Strasse 44, 39120 Magdeburg, Germany. bild.neurochirurgie@uni-magdeburg.de
Insights
Traumatic brain stem lesions (tBSL) are common in children with severe head injuries, detected by MRI. These lesions significantly impact coma duration and outcomes, with bilateral pons or medulla lesions leading to 100% mortality.
Area of Science:
- Pediatric Neurology
- Neuroradiology
- Trauma Surgery
Background:
- Traumatic brain stem lesions (tBSL) are considered rare in pediatric head injuries.
- Computed tomography (CT) often fails to detect these subtle lesions.
- Early detection is crucial for predicting outcomes.
Purpose of the Study:
- To determine the frequency and significance of tBSL in children with severe head injuries.
- To evaluate the utility of early magnetic resonance imaging (MRI) in identifying tBSL.
- To compare the incidence and distribution of tBSL in children and adults.
Main Methods:
- Prospective study of 30 consecutive children with severe head injuries.
- MRI scans performed within 8 days of injury.
- Correlation of tBSL findings with coma duration and Glasgow Outcome Score.
Main Results:
- The incidence of tBSL was found to be 60% in the studied pediatric population.
- Bilateral lesions in the pons or medulla oblongata were associated with 100% mortality.
- tBSL presence significantly correlated with longer coma duration and poorer outcomes.
Conclusions:
- Early MRI is highly valuable for detecting tBSL in pediatric head injuries.
- The frequency and distribution of tBSL in children resemble those observed in adults.
- MRI findings aid in predicting patient outcomes after severe head trauma.
Introduction:
Traumatic brain stem lesions (tBSL) in children are thought to be a rare phenomenon. This prospective study analyzed the frequency and significance of such lesions on early magnetic resonance imaging (MRI) after severe head injury, since CT fails to demonstrate these lesions.
Methods:
In 30 consecutive children comatose after head injuries, MRI was performed within 8 days of the injury.
Results:
The incidence of tBSL was 60%. When the lesion affected the pons or caudal portions of medulla oblongata bilaterally, mortality was 100%. The presence of tBSL significantly correlated with the duration of coma and the categories of outcome, as indicated by the Glasgow Outcome Score. The frequency and the distribution of tBSL in children were similar to adults.
Conclusion:
Magnetic resonance imaging appears to be of high predictive value after severe pediatric head injuries.
Related Concept Videos
Brainstem
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
Brain Abscess l: Introduction
Traumatic Brain Injury l: Introduction
Secondary Spinal Cord Injury llI: Pathophysiology

