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Updated: Jul 20, 2026

Microscopic Replantation of Penile Glans Amputation Due to Circumcision
Published on: June 3, 2022
[Syphilitic penile pseudotumor. Report of a case]
J Herrera Puerto1, C Herrera Flores, C López Elzaurdia
1Servicio de Urología, Hospital Ntra. Sra. de Sonsoles, Avila.
This case study highlights a rare presentation of secondary syphilis as a penile mass. Prompt diagnosis and antibiotic treatment led to a full recovery, underscoring the importance of considering syphilis in genital ulcer disease.
Area of Science:
- Urology
- Dermatology
- Infectious Diseases
Background:
- Syphilis, a sexually transmitted infection, is experiencing a global resurgence.
- Genital manifestations of secondary syphilis can be diverse and atypical.
Observation:
- A patient presented with a solid penile mass, an unusual symptom for secondary syphilis.
- Clinical presentation, histology, and lab tests were crucial for diagnosis.
Findings:
- The patient was diagnosed with secondary syphilis presenting as a genital lesion.
- The condition responded well to standard antibiotic therapy.
Implications:
- This case emphasizes the need for a high index of suspicion for syphilis in patients with atypical genital ulcers.
- Understanding diverse syphilitic presentations is vital for effective diagnosis and management of genital ulcer disease.
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