Extrarenal manifestations of cystic kidney disease

Cystic disorders of the kidney may manifest their presence not only through renal but also through systemic signs and symptoms. Extrarenal manifestations include cerebral aneurysms, hepatic cysts, hepatic fibrosis, polycythemia, and retinal changes. Awareness of such associations strengthens the likelihood that renal cystic disease will be detected in its earlier stages. Involvement of organs other than the kidneys takes on added significance as the lives of affected individuals are prolonged through dialysis and renal transplantation.