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Published on: May 26, 2023
Mitral valve surgery and acute renal injury: port access versus median sternotomy
Brian J McCreath1, Madhav Swaminathan, John V Booth
1Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Background:
Many outcomes and complications of minimally invasive and conventional cardiac surgery await comparison. Patients undergoing mitral valve surgery commonly sustain renal injury. Using peak postoperative fractional change of serum creatinine as a marker of renal injury, we tested the hypothesis that mitral valve surgery with port access minithoracotomy (Port) and conventional surgery with a median sternotomy (MS) incision are associated with different degrees of acute renal injury.
Methods:
We evaluated data from all isolated mitral valve operations by a single surgeon between 1990 and 2000 (MS = 90, Port = 227). We also performed a secondary analysis of mitral valve surgeries performed by both MS and Port approaches in a concurrent period from 1996 to 2002 (MS = 93, Port = 240). Univariable and multivariable tests were used to determine the association of surgical technique with peak postoperative creatinine (CrmaxPost) and peak postoperative fractional change in creatinine (%deltaCr); p less than 0.05 was considered significant.
Results:
In our analysis that accounted for the date of surgery, we observed a highly significant independent association between surgical approach and %deltaCr, indicating a greater risk of acute renal injury in the MS group (F value 13.33; p = 0.0003). Similar findings were noted in the secondary (time-concurrent) analysis of %deltaCr (F value 12.65; p = 0.0176).
Conclusions:
We present retrospective evidence of reduced acute renal injury associated with the port access technique in mitral valve surgery patients. Our findings suggest that a port access minithoracotomy approach to mitral valve surgery may be preferable to conventional methods for patients with high renal risk.
Insights
Minimally invasive mitral valve surgery using port access minithoracotomy significantly reduces acute kidney injury compared to conventional median sternotomy. This finding suggests port access may be preferable for high-risk renal patients.
Area of Science:
- Cardiac Surgery
- Nephrology
- Minimally Invasive Surgery
Background:
- Mitral valve surgery, both conventional and minimally invasive, can lead to renal complications.
- Acute kidney injury is a common concern following cardiac procedures.
- Comparing surgical techniques is crucial for optimizing patient outcomes.
Purpose of the Study:
- To compare the degree of acute renal injury between port access minithoracotomy and conventional median sternotomy for mitral valve surgery.
- To test the hypothesis that surgical approach impacts renal injury markers.
Main Methods:
- Retrospective analysis of isolated mitral valve operations (1990-2000 and 1996-2002).
- Evaluation of peak postoperative fractional change in serum creatinine (%deltaCr) as a renal injury marker.
- Statistical analysis using univariable and multivariable tests.
Main Results:
- A significant independent association was found between surgical approach and %deltaCr.
- The median sternotomy (MS) group showed a significantly greater risk of acute renal injury compared to the port access (Port) group.
- This association was consistent in both primary and secondary analyses.
Conclusions:
- Retrospective data indicate reduced acute renal injury with the port access technique in mitral valve surgery.
- Port access minithoracotomy may be a preferred approach over conventional median sternotomy for patients with elevated renal risk.
- Further research may validate these findings for improved patient selection and surgical strategy.
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