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Updated: Oct 2, 2026

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens
Published on: April 18, 2013
[Descriptive anatomical study of the major coronary trunks and the principal epicardial collaterals. 125 cases]
Insights
Rare left coronary artery abnormalities, including trunk absence and intraparietal segments of the anterior interventricular artery, can mimic stenosis. Understanding these variations is crucial for accurate diagnosis and treatment planning in coronary artery disease.
Area of Science:
- Cardiovascular Anatomy
- Interventional Cardiology
Context:
- Congenital coronary artery anomalies are infrequent but can significantly impact cardiac function and surgical planning.
- Variations in coronary artery origins and courses, particularly involving the left coronary artery, require detailed understanding for accurate interpretation of diagnostic imaging.
Purpose:
- To describe rare abnormalities in the origin and course of the left coronary artery and its branches.
- To highlight potential diagnostic challenges, such as differentiating intraparietal segments from stenosis or spasm.
- To assess the suitability of major left coronary artery branches for aortocoronary bypass grafting.
Summary:
- Abnormalities at the left coronary artery origin include trunk absence and variations in the anterior interventricular artery's intraparietal course (17% of cases), which can be misdiagnosed as stenosis or spasm.
- Short posterior interventricular arteries (6% of cases) receiving collaterals from the right coronary artery can affect bypass graft efficacy.
- The left first diagonal and marginal arteries are often suitable for aortocoronary bypass grafting in over one-third of individuals.
Impact:
- Accurate identification of these coronary artery anomalies improves diagnostic precision, preventing misinterpretation of imaging studies.
- Understanding these anatomical variations aids in optimizing surgical strategies, particularly for coronary artery bypass grafting.
- This knowledge contributes to better patient management and outcomes in cardiovascular interventions.
Abstract:
Abnormalities at the origin are rare and involve only the left coronary artery: absence of the trunk of this artery in 3 cases, as a result of separation of the origins of the anterior interventricular and the left circumflex. As far as course is concerned, the principal abnormality involves the anterior interventricular: presence in 17% of cases of an intraparietal segment, quite narrow and with a thin wall which is remarkably fixed and constant in its different characteristics: rapid reading of a film taken during selective injection may lead to a conclusion of stenosis or to that of a non-existent spasm. In 6% of cases, the posterior interventricular is short, joined to the middle part of the posterior interventricular sulcus by a collateral of the right coronary. Thus in the case of a long stenosis of the right coronary artery, right aorto-coronary by-pass, distal, provides no blood supply to the postero-inferior part of the septum and the posterior part of the apex. In more than one third of cases the left first diagonal and marginal arteries are of sufficient calibre to permit implantation of an aorto-coronary graft.
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