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Updated: Sep 26, 2026
Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD
Published on: October 10, 2012
[Blood corticosterone concentration and differential leukocyte count in stressed Norway rats with different modes of
1Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, pr. akademika Lavrent'eva 10, Novosibirsk, 630090 Russia. koleso@bionet.ncs.ru
Abstract:
We studied dynamics of leukocyte composition and corticosterone content in the peripheral blood of male Norway rats after long-term selection for tame or aggressive behavior immediately after 20 min restrain as well as 2 and 4 h later. The stressor changed the stressor concentration and the proportion of various types of leukocytes in the both experimental groups. Quantitatively, the changes were more pronounced in the group of aggressive animals.
