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Updated: Sep 26, 2026

Evaluating Therapeutic and Chemical Toxicity Using Organ-Cultured Porcine Corneas and Epithelial Wound Healing
Published on: January 10, 2025
Tissue adhesive to treat 2-site corneal melting associated with topical ketorolac use
Alexandre S Marcon1, Christopher J Rapuano, Janine G Tabas
1Cornea, Wills Eye Hospital, Department of Ophthalmology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Abstract:
We report a case of a 78-year-old man presenting with 2 discrete areas of sterile corneal melting associated with chronic use of topical ketorolac after uneventful clear corneal phacoemulsification. He was treated successfully with tissue adhesive application. Patients receiving chronic topical ketorolac treatment, especially those with ocular surface abnormalities, can present with severe complications such as corneal melting.

