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Increasing stroke incidence and decreasing case fatality, 1989-1998: a study from the stroke register in Malmö,
Hélène Pessah-Rasmussen1, Gunnar Engström, Ingela Jerntorp
1Department of Neurology, Malmö University Hospital, Sweden. Helene.pessah-rasmussen@skane.se
Background And Purpose:
Although the incidence of and mortality from myocardial infarction (MI) have declined in most industrialized countries, incidence studies of stroke have shown less consistent trends. This study examines time trends in the incidence of stroke and case fatality rates in relation to socioeconomic circumstances and history of MI.
Methods:
Stroke incidence in the city of Malmö, Sweden (250,000 citizens), has been continuously monitored since 1989. All patients 50 to 79 years of age who experienced a first-ever stroke between 1989 and 1998 were included.
Results:
We included 3621 patients (1969 men, 1652 women). The age-standardized incidence was 647 per 100,000 persons-years for men and 400 per 100,000 persons-years for women. The annual increase-3.1% in men (P<0.05) and 2.9% in women (P<0.05)-was more pronounced in the younger age groups and was lowest in areas with poor socioeconomic circumstances. We found that 13% of the men and 6% of the women had a history of MI; this proportion was stable over the study period. The average case fatality rates in 1989 to 1998 were 10% for men and 9.3% for women. Rates remained stable for men but declined significantly in women (odds ratio per year, 0.895; 95% confidence interval, 0.84 to 0.95).
Conclusions:
In this urban population, stroke incidence increased between 1989 and 1998. The rate of increase tended to be lower in residential areas with least favorable socioeconomic circumstances. The proportion with a history of MI remained unchanged during the study period. There has been significant improvement in the case fatality rate in women but not in men.
Insights
Stroke incidence increased in Malmö from 1989-1998, particularly in younger individuals and less socioeconomically deprived areas. Case fatality rates improved for women but not men.
Area of Science:
- Epidemiology
- Cardiovascular Research
- Public Health
Background:
- Myocardial infarction (MI) incidence and mortality have declined in industrialized nations.
- Stroke incidence trends are less consistent globally.
- Socioeconomic factors may influence stroke incidence and outcomes.
Purpose of the Study:
- To examine time trends in stroke incidence.
- To analyze stroke case fatality rates.
- To investigate the relationship between stroke trends, socioeconomic status, and history of MI.
Main Methods:
- Continuous monitoring of stroke incidence in Malmö, Sweden (250,000 citizens) from 1989 to 1998.
- Inclusion of all first-ever stroke patients aged 50–79 years.
- Analysis of age-standardized incidence, case fatality rates, and proportion with prior MI.
Main Results:
- Age-standardized stroke incidence was 647/100,000 for men and 400/100,000 for women.
- Annual incidence increased by 3.1% in men and 2.9% in women, more in younger age groups.
- Incidence increase was lowest in socioeconomically deprived areas; prior MI history was stable; case fatality declined significantly in women (OR 0.895/year) but not men.
Conclusions:
- Stroke incidence rose in this urban population between 1989 and 1998.
- The rate of increase in stroke incidence was lower in areas with less favorable socioeconomic circumstances.
- While stroke case fatality improved significantly for women, no significant improvement was observed for men during the study period.
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