[A case of primary hepatic lymphoma successfully treated by THP-COP therapy]

A 65-year-old woman was admitted due to epigastralgia. The presence of a tumor mass in the umbilical portion of the liver was recognized by abdominal ultrasonography and computed tomography scan. Needle biopsy of the tumor showed non Hodgkin's lymphoma (diffuse large B cell type) by histology and histoimmunology. She was treated by the THP-COP protocol, and complete remission was achieved after the third cycle. Primary hepatic lymphoma is so infrequent that standard treatments are not established yet. Most cases of primary hepatic lymphoma are treated by surgical resection in Japan; however our conservative approach to remission is considered as very helpful for discussing how to treat primary hepatic lymphoma.