Related Experiment Video
Updated: Sep 26, 2026
Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Pathogenesis of varicose veins
1The Vascular Biology Unit, Department of Surgery, School of Medicine, James Cook University, Townsville, Queensland, Australia, 4811.
Background:
varicose veins are present in up to 40% of the population. They may be associated with considerable morbidity. Around 70% of patients with chronic venous insufficiency have evidence of superficial venous incompetence on duplex imaging.
Methods:
in this publication we review the evidence available regarding the pathogenesis of varicose veins.
Results:
a number of theories have been suggested. The present data suggests that abnormalities in the venous endothelium and smooth muscle cells result in vein wall dilatation with secondary valvular incompetence. However, there is also evidence to support acquired venous valve failure. Congenital venous valve abnormalities have not been well studied.
Conclusion:
further work is required on this relatively neglected topic. The use of improved imaging such as high-resolution ultrasound is likely to significantly improve our understanding of venous valve function and pathology.
More Related Videos
Related Concept Videos
01:26Varicose Veins I: Introduction
01:26Varicose Veins II: Diagnostic Studies and Interprofessional Care
01:30Venous Thrombosis I: Introduction
01:24Esophageal Varices-I: Introduction
01:20Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
01:15Veins of Lower Limbs
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the knee,...