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Updated: Aug 11, 2026

A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research
Published on: August 16, 2017
Gene expression data preprocessing
J Herrero1, R Díaz-Uriarte, J Dopazo
1Unidad de Bioinformática, Centro Nacional de Investigaciones Oncológicas (CNIO), Melchor Fernández Almagro, 3 28029 Madrid, Spain.
Abstract:
We present an interactive web tool for preprocessing microarray gene expression data. It analyses the data, suggests the most appropriate transformations and proceeds with them after user agreement. The normal preprocessing steps include scale transformations, management of missing values, replicate handling, flat pattern filtering and pattern standardization and they are required before performing any pattern analysis. The processed data set can be sent to other pattern analysis tools.

