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Sweet's syndrome-like blastomycosis.

Anne Wilkerson¹, Roy King, Paul B Googe

¹Department of Pathology, Vanderbilt University, Nashville, Tennessee, USA.

The American Journal of Dermatopathology

|March 26, 2003

Summary

This summary is machine-generated.

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North American blastomycosis can present atypically. This case highlights a patient whose skin lesions mimicked Sweets syndrome but were confirmed to be blastomycosis.

Area of Science:

Mycology
Dermatopathology
Infectious Diseases

Background:

Cutaneous North American blastomycosis typically presents with verrucous nodules.
Histological hallmarks include pseudoepitheliomatous hyperplasia and neutrophilic microabscesses.

Observation:

A patient presented with erythematous nodules and plaques resembling Sweets syndrome.
Histopathology revealed a diffuse neutrophilic infiltrate without epidermal hyperplasia.

Findings:

Microscopic examination identified scattered histiocytes and multinucleated giant cells.
Fungal stains confirmed the presence of budding yeast forms consistent with Blastomyces sp.

Implications:

This case expands the clinical and histological spectrum of cutaneous blastomycosis.

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It underscores the importance of considering fungal infections in differential diagnoses of inflammatory dermatoses.