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[Is respiratory syncytial virus one of the causative agents for transient hyperphosphatasemia?]
1Department of Pediatrics, Kishiwada City Hospital, Kishiwada City, Osaka 596-8501.
Objective:
In the winter of 2001, we found several cases of transient hyperphosphatasemia (TH) in patients with respiratory syncytial virus (RSV) infection. Therefore, we tried to verify that RSV was one of the causative agents for TH.
Results:
From November 2001 to January 2002, we diagnosed 94 cases of RSV infection with the detection of virus antigens in the nasal mucus. Among these cases, we found six cases (6.4%) of TH, and all six patients were over one year of age. There were 55 cases of RSV infection in patients over one year of age, and the rate of TH with RSV infection was estimated to be 10.9% in this age group. This rate of TH (6.4%) was significantly higher than rates reported in previous studies (0.33% to 1.5%, p = 0.0145 to p < 0.0001).
Conclusion:
We conclude that RSV is one of the causative agents for TH.