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[Roles of molecular analysis in hematopoietic stem cell transplantation]
Masayuki Hino1, Ryosuke Yamamura, Keizo Fujino
1Department of Internal Medicine, Osaka City University Medical School.
Abstract:
Recent advances in molecular analysis by polymerase chain reaction(PCR) have taken a prominent position an essential part in regeneration medicine. In hematopoietic stem cell transplantation, HLA(human leukocyte antigen) typing, assessment of graft viability/rejection (chimerism analysis), and evaluation of minimal residual disease are significant for treatment strategy. Molecular analysis will play a more important role in the diversification of transplantation methods in the future of tailor-made medicines.