Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Canalization, developmental stability, and morphological integration in primate limbs.

Benedikt Hallgrímsson1, Katherine Willmore, Brian K Hall

  • 1Department of Cell Biology and Anatomy, University of Calgary, Calgary, Alberta T2N 4N1, Canada. bhallgri@ucalgary.ca

American Journal of Physical Anthropology
|March 26, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Revisiting the Palimpsest: Exploring the Interaction of the Variance and Structure of Developmental Determinants of Phenotypic Covariance.

Integrative and comparative biology·2026
Same author

Three-dimensional cellular dynamics and mandibular morphogenesis.

Frontiers in cell and developmental biology·2026
Same author

Using end-to-end attribution to link greenhouse gas emitters to child health outcomes.

Archives of disease in childhood·2026
Same author

COMPREHENSIVE GENETIC INVESTIGATION REVEALS HETEROGENEOUS PATHWAYS TO OBSTRUCTIVE SLEEP APNEA.

medRxiv : the preprint server for health sciences·2026
Same author

The role of sagittal maxillary-mandibular relationships on perceptions of facial shape esthetics: A three-dimensional morphometric analysis.

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics·2026
Same author

The craniofacial shape of modern humans embodies genomic signatures of evolution, diversity, and clinical conditions.

bioRxiv : the preprint server for biology·2026
Same journal

A geometric morphometric assessment of shape variation in adult pelvic morphology.

American journal of physical anthropology·2021
Same journal

Corrigendum: Infanticide in chimpanzees: Taphonomic case studies from Gombe.

American journal of physical anthropology·2021
Same journal

Sexual dimorphism in the size and shape of the non-obstetric pelvis across anthropoids.

American journal of physical anthropology·2021
Same journal

The biological index of frailty: A new index for the assessment of frailty in human skeletal remains.

American journal of physical anthropology·2021
Same journal

Mass violence in Copper Age Europe: The massacre burial site from Potočani, Croatia.

American journal of physical anthropology·2021
Same journal

Skeletal evidence of structural violence among undocumented migrants from Mexico and Central America.

American journal of physical anthropology·2021
See all related articles

Developmental stability and canalization influence evolution. Limb variability increases distally in macaques due to postnatal factors, while heritability and fluctuating asymmetry correlate in mice, suggesting linked developmental mechanisms.

Area of Science:

  • Evolutionary developmental biology
  • Primate and human evolution

Background:

  • Canalization, developmental stability, and morphological integration are key properties of developmental systems.
  • These phenomena influence the interplay between development and evolution.
  • Understanding these concepts is crucial for studying primate and human evolution.

Purpose of the Study:

  • To review canalization, developmental stability, and morphological integration in primate and human evolution.
  • To test hypotheses on variability patterning in mammalian limbs.
  • To investigate the relationship between heritability, fluctuating asymmetry, and morphological integration.

Main Methods:

  • Analysis of environmental variances and fluctuating asymmetries (FA) in macaque and fetal mouse limbs.

Related Experiment Videos

  • Comparison of heritability and FA across different limb measurements in fetal mice.
  • Examination of covariation structure in fore- and hindlimb skeletal elements.

    • Main Results:

    • Environmental variances and FA increase distally in adult macaque limbs, attributed to postnatal mechanical effects.
    • Heritability and FA are significantly correlated in fetal mouse limbs, indicating related developmental stability mechanisms.
    • Covariation patterns reveal morphological integration between fore- and hindlimb skeletal elements, suggesting developmental modules.

    Conclusions:

    • Postnatal mechanical factors influence limb variability in primates.
    • Heritability and developmental stability mechanisms are linked.
    • Developmental modules integrate structures between primate forelimbs and hindlimbs, requiring selection to overcome for divergence.