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Benign subarachnoid space enlargement of infancy

R O Suara1, A J Trouth, M Collins

  • 1Department of Pediatrics and Child Health, Howard University Hospital Washington, DC, USA.

Insights

Subarachnoid space enlargement in infants is a benign condition causing rapid head growth but normal development. This fluid collection typically resolves by age two, though head circumference may remain large.

Area of Science:

  • Pediatric Neurology
  • Neuroradiology

Background:

  • Subarachnoid space enlargement is a recognized benign condition.
  • Characterized by rapid head enlargement in infants with normal neurodevelopment.

Observation:

  • Two infants presented with rapid increases in head circumference.
  • Both had family histories of macrocephaly and normal neurodevelopment.
  • Radiologic imaging revealed subarachnoid space fluid collection with normal ventricular size.

Findings:

  • Both infants experienced a benign clinical course.
  • Subarachnoid fluid collection resolved by the second year of life.
  • Head circumference remained at or above the 95th percentile post-resolution.

Implications:

  • Highlights the importance of recognizing subarachnoid space enlargement as a benign entity.
  • Informs pediatricians about the typical resolution and long-term head circumference findings.
  • Aids in differentiating this condition from more serious causes of macrocephaly.

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