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Thirty-one cases of Marjolin's ulcer
1Plastic and Reconstructive Surgery Department, Medical Faculty, Adnan Menderes University, Aydin, Turkey. copcu@mailcity.com
Clinical and Experimental Dermatology
|March 26, 2003
Summary
Marjolin's ulcer, a rare skin cancer after burns, occurred in 31 of 264 cases. This aggressive malignancy typically develops 19 years post-burn, often as squamous cell carcinoma.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Marjolin's ulcer is a rare, aggressive skin malignancy.
- It arises in skin with prior trauma or chronic inflammation, especially burns.
Purpose of the Study:
- To determine the frequency and clinicopathological features of Marjolin's ulcer.
- To assess its significance as a post-burn complication.
Main Methods:
- Retrospective review of 264 burn cases.
- Analysis of 31 confirmed Marjolin's ulcer cases and 14 non-malignant ulcers.
Main Results:
- 31 cases of Marjolin's ulcer identified.
- Average time from burn to ulceration was 19 years.
- Most were squamous cell carcinomas; some spread to lymph nodes but not distantly.
Conclusions:
- Marjolin's ulcer is a significant, albeit rare, complication following burns.
- Early recognition and management are crucial for this aggressive skin cancer.