Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Benign cutaneous Degos' disease.

R M Ojeda Cuchillero1, M Sánchez Regaña, P Umbert Millet

  • 1Department of Dermatology, Hospital Sagrado Corazón, Teaching Unit of University of Barcelona, Barcelona, Spain. ireuamu@retemail.es

Clinical and Experimental Dermatology
|March 26, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Study on the use of omega-3 fatty acids as a therapeutic supplement in treatment of psoriasis.

Clinical, cosmetic and investigational dermatology·2011
Same author

[Bullous scabies responding to ivermectin therapy].

Actas dermo-sifiliograficas·2010
Same author

Nail psoriasis: a combined treatment with 8% clobetasol nail lacquer and tacalcitol ointment.

Journal of the European Academy of Dermatology and Venereology : JEADV·2008
Same author

Topical tacrolimus for the treatment of psoriasis on the face, genitalia, intertriginous areas and corporal plaques.

Journal of drugs in dermatology : JDD·2006
Same author

Elevated serum parathyroid hormone levels in a patient with annular pustular psoriasis.

Journal of the European Academy of Dermatology and Venereology : JEADV·2005
Same author

Clinical experience with the use of cyclosporin A in psoriasis. Results of a retrospective study.

The Journal of dermatological treatment·2005

Malignant atrophic papulosis, a rare vaso-occlusive disorder, involves skin and organ thrombosis. A case study suggests antiplatelet therapy may be effective for the benign cutaneous form, showing no systemic involvement over 8 years.

Area of Science:

  • Vascular Medicine
  • Dermatology
  • Pathology

Background:

  • Malignant atrophic papulosis (MAP) is a rare systemic vaso-occlusive disorder.
  • Characterized by thrombosis in dermal, gastrointestinal, and central nervous system vessels.
  • Pathogenesis is linked to endothelial cell damage; no effective treatment exists.

Observation:

  • A 26-year-old male presented with clinical and histologic features of Degos' disease.
  • The patient exhibited cutaneous lesions with central necrosis and porcelain-like scarring.
  • No systemic involvement was noted during an 8-year follow-up.

Findings:

  • The patient responded well to antiplatelet therapy.
  • This case suggests a potential therapeutic option for Degos' disease.

Related Experiment Videos

  • Absence of systemic involvement indicates a possible benign presentation.

    • Implications:

    • Antiplatelet therapy may be a viable treatment for benign cutaneous Degos' disease.
    • This case highlights the importance of considering less severe forms of MAP.
    • Further research into endothelial cell damage and targeted therapies is warranted.