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[A clinical study of reflux oesophagites]
Jiali Jiang1, Hong Wang, Minli Wang
1Department of Digestion, Beijing Tongren Hospital, Capital University of Medical Science, Beijing 100730, China.
Objective:
To study the incidence and role of acid and bile reflux in gastroesophageal reflux disease (GERD).
Methods:
Fifty two patients with reflux symptoms were studied. All of them were performed endoscopy received acid and bile reflux monitoring.
Results:
Fifty two patients received acid and bile reflux monitoring, 42 patients had reflux with the main type of double-reflux (both acid and bile reflux) which was 59.5% (25/42), and with the type of the single-reflux which was 40.5% (17/42). Among single-reflux, the acid reflux was the main type about 76.4% (13/17); Among double-reflux, the degree of acid reflux was more severe, than did bile reflux; The percent of reflux oesophagites join the double-reflux patients was significant high than that in single-acid-reflux patients (P < 0.05); There was a liner correlation between acid reflux index either the frequency or the severity of reflux symptoms.
Conclusions:
Double-reflux was the main type of reflux in GERD, and acid reflux was the main type among double-reflux and single-reflux. There may be a synergistic effect between acid and bile reflux. Acid reflux was the main factor for reflux symptoms.