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Prostate mucinous adenocarcinoma with signet ring cell
Eyup Gumus1, Banu Yilmaz, Cengiz Miroglu
1Second Urology Clinic, Sisli Etfal Teaching Hospital, 15/5 81130, Uskudar, Istanbul, Turkey. eyupg@superonline.com
Summary
This report details the 12th known case of a rare prostate mucinous adenocarcinoma with signet ring cells. The patient showed no signs of recurrence 27 months after radiotherapy.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Prostate mucinous adenocarcinoma with signet ring cell is an extremely rare neoplasm.
- Only 11 cases have been documented in medical literature prior to this report.
Observation:
- A 47-year-old male patient presented with urethrostenosis requiring urethrotomy.
- An incidental lesion in the prostatic urethra was discovered during cystoscopy.
- Endoscopic examination revealed a spongy, gray-white mass in the prostatic urethra.
Findings:
- Biopsy confirmed the diagnosis of prostate mucinous adenocarcinoma with signet ring cell.
- The patient received a total of 50 Gy radiotherapy.
- Follow-up at 27 months showed normal thoracoabdominal computed tomography, bone scintigraphy, and tumor markers (PSA, CEA, CA19-9).
Implications:
- This case adds to the limited understanding of prostate mucinous adenocarcinoma with signet ring cell.
- Successful treatment with radiotherapy suggests a potential therapeutic option for this rare cancer.
- Long-term monitoring is crucial for patients diagnosed with this rare prostate cancer.