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Adsorbed surfactants for affinity chromatography. end-group modification of ethylene glycol polymers
Cemile Yaniç1, Martin W Bredenkamp, Edmund P Jacobs
1Institute of Polymer Science, Stellenbosch University, Matieland, South Africa.
Bioorganic & Medicinal Chemistry Letters
|March 27, 2003
Abstract:
The hydroxyl end-groups of Pluronic F108 [a tri-block copolymer surfactant of poly(ethylene glycol) and poly(propylene glycol) [PEG-PPG-PEG]] were converted into primary amine and quaternary ammonium equivalents for use in a new approach to affinity chromatography. The preparation of sulphonic acid end-groups was also attempted.