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Toxicokinetics of nortriptyline and amitriptyline: two case reports

E J F Franssen1, P W A Kunst, P M Bet

  • 1Department of Pharmacy, University Hospital, Vrije Universiteit, Amsterdam, The Netherlands. EJF.Franssen@vumc.nl

Therapeutic Drug Monitoring
|March 27, 2003
PubMed
Summary

Severe overdoses of tricyclic antidepressants (TCAs) like nortriptyline and amitriptyline show stereoselective metabolite profiles. Prompt supportive care can lead to survival despite poor prognostic markers in TCA toxicity.

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