Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mesenteric hemodynamic response to circulatory shock.

Eugene P Ceppa1, Katherine C Fuh, Gregory B Bulkley

  • 1Department of Surgery, The Johns Hopkins Hospital, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287-4685, USA.

Current Opinion in Critical Care
|March 27, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Minimally invasive repair of iatrogenic bile duct injuries: a systematic review and meta-analysis.

Surgical endoscopy·2026
Same author

Correction: Minimally invasive repair of iatrogenic bile duct injuries: a systematic review and meta-analysis.

Surgical endoscopy·2026
Same author

Endoscopic Management of Bile Leaks After Subtotal Versus Total Laparoscopic Cholecystectomy: A Single Center Comparative Analysis.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract·2026
Same author

Postpancreatectomy acute pancreatitis: a United States national perspective.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract·2026
Same author

Correction: GAS6/AXL Inhibition Enhances Ovarian Cancer Sensitivity to Chemotherapy and PARP Inhibition through Increased DNA Damage and Enhanced Replication Stress.

Molecular cancer research : MCR·2026
Same author

Approaches to optimize the benefits of immunotherapy and immunotherapy combinations across endometrial cancer types.

Journal of the National Cancer Institute·2026

Circulatory shock causes asymmetrical mesenteric hemodynamic responses, leading to organ damage. Mesenteric vasoconstriction sustains cardiac output but can cause gastrointestinal and organ injuries, potentially triggering multiple organ failure.

Area of Science:

  • Physiology
  • Pathophysiology
  • Gastroenterology

Background:

  • The mesenteric hemodynamic response to circulatory shock is substantial and asymmetrical.
  • Vasoconstriction disproportionately affects mesenteric organs, impacting nutrient flow.

Purpose of the Study:

  • To review the mesenteric hemodynamic response during circulatory shock.
  • To elucidate the consequences of mesenteric vasoconstriction on organ perfusion and integrity.

Main Methods:

  • Review of existing literature on circulatory shock and mesenteric hemodynamics.
  • Analysis of physiological responses in hemorrhagic, cardiogenic, and septic shock.

Main Results:

  • Circulatory shock triggers mesenteric vasoconstriction to sustain cardiac output via autotransfusion.

Related Experiment Videos

  • Mesenteric arterioles constrict to maintain vital organ perfusion at the expense of mesenteric organs.
  • Septic shock presents variable mesenteric blood flow but increased oxygen consumption.

    • Conclusions:

    • Shock-induced mesenteric injury can lead to gastric stress erosions, mesenteric ischemia, and ischemic organ damage.
    • Mesenteric organ injury can initiate systemic inflammatory response syndrome and multiple organ failure.