Related Experiment Video
Updated: Sep 26, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[Scintigraphic findings in a patient with sickle-cell thalassemia and recurrent pain attacks]
Peter Mikosch1, Barbara Jauk, Wilhelm Kaulfersch
1Abteilung für Nuklearmedizin und Endokrinologie, Landeskrankenhaus Klagenfurt, St. Veiterstrasse 47, A-9020 Klagenfurt. Peter.Mikosch@lkh-klu.at
Abstract:
The case of an eight years old African boy who suffers from sickle cell-thalassemia is presented. In the course of the disease frequent pain attacks occurred within the abdomen and extremities, recently also within the trunk. Local pain, at some occasions in combination with local swelling and always positive laboratory parameters for inflammation, hindered a solely clinical differentiation between bone infarcts and osteomyelitis. Bone scintigraphy, eventually in combination with bone marrow scintigraphy, can assist the clinician in the differentiation of aseptic bone infarcts versus secondary osteomyelitis. Based on the presented case scintigraphic results for bone infarcts, osteomyelitis and special scintigraphic pattern seen in sickle cell disease are presented. Furthermore, problems regarding the interpretation of the scintigraphies in relation to the delayed time after the beginning of pain attacks are discussed.
Related Concept Videos
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
