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Updated: Sep 26, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
Catechols from abietic acid synthesis and evaluation as bioactive compounds
B Gigante1, C Santos, A M Silva
1INETI, Departamento de Tecnologia de Indústrias Qui;micas, Estrada do Paço do Lumiar, 22, 1649-038 Lisbon, Portugal. barbara.gigante@ineti.pt
Abstract:
Catechols from abietic acid were prepared by a short and good yielding chemical process and further evaluated for several biological activities namely, antifungal, antitumoral, antimutagenic, antiviral, antiproliferative and inhibition of nitric oxide. Their properties were compared with those of carnosic acid (6), a naturally occurring catechol with an abietane skeleton and known to possess potent antioxidant activity, as well as anticancer and antiviral properties. From all the synthetic catechols tested compound 2 showed the best activities, stronger than carnosic acid.
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