Neuraminidase treatment enhances the lysolecithin induced intercellular adhesion of amoeba proteus

Egg lysolecithin induces intercellular adhesion of Amoeba proteus. Pre-treatment of cells with Vibrio cholerae neuraminidase (VCN) increases the adhesive property of cells as was evidenced in their formation of larger cell aggregates than controls. A possible role of VCN exposed receptor sites in cellular adhesion is suggested.