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Updated: Aug 19, 2026

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
Published on: January 12, 2022
[Tubulo-interstitial nephritis and uveitis (TINU syndrome): a new pediatric case]
D Bensmail1, I Rossignol, E Tuil
1Service de Médecine Interne, Centre Hospitalier National d'Ophthalmologie des Quinze-Vingts, Paris.
Abstract:
TINU is a rare disease of unknown etiology that associates acute tubulointerstitial nephritis and uveitis in a context of systemic symptoms (asthenia, weight loss, fever) and inflammatory biological signs. We report a new case in a 10-year-old girl with unilateral uveopapillitis and renal insufficiency caused by interstitial nephritis (creatininemia: 225 micro mol/l). Complete recovery was obtained with high-dose systemic corticotherapy, with the patient remaining free of disease 2.5 years after the end of treatment. The disappearance of renal lesions was histologically verified.
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