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Updated: Aug 15, 2026

Assessing Bacterial Invasion of Cardiac Cells in Culture and Heart Colonization in Infected Mice Using Listeria monocytogenes
Published on: May 27, 2015
[A man with Campylobacter endocarditis, treatable as Campylobacter fetus following identification]
P L Wong1, G Fedder, F G C Heilmann
1Afd. Interne Geneeskunde, Gelre Ziekenhuizen, locatie Lukas, Apeldoorn.
Abstract:
A 48-year-old Dutch patient presented with general malaise, recurrent fever and weight loss. Routine cultures identified a Campylobacter in two blood cultures. When initial treatment with clarithromycin failed, the patient developed endocarditis. DNA sequencing identified Campylobacter fetus subspecies fetus (C. fetus). The patient recovered after treatment of the infection with imipenem and gentamycin, based on the minimal inhibiting concentration. C. fetus is a rare cause of infection in humans and is mostly transmitted by handling infected animal material. The patient contracted the infection as a result of a puncture accident with a butcher's knife about a year previously whilst working in a slaughterhouse.
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