Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Leflunomide.

S B Cohen1, I Iqbal

  • 1St Paul University Medical Center, Dallas, Texas, USA.

International Journal of Clinical Practice
|March 29, 2003
PubMed
Summary
This summary is machine-generated.

Leflunomide (Arava) effectively treats rheumatoid arthritis, as confirmed by pivotal clinical trials and post-release data. This report details its efficacy and safety profile in managing this autoimmune condition.

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of a machine learning tool for the early identification of patients with undiagnosed psoriatic arthritis - A retrospective population-based study.

Journal of translational autoimmunity·2023
Same author

Assessing vaccine-mediated protection in an ultra-low dose <i>Mycobacterium tuberculosis</i> murine model.

bioRxiv : the preprint server for biology·2023
Same author

Correction to: PANLAR consensus statement on biosimilars.

Clinical rheumatology·2019
Same author

PANLAR consensus statement on biosimilars.

Clinical rheumatology·2019
Same author

Safety, pharmacokinetics, and pharmacodynamics of RSLV-132, an RNase-Fc fusion protein in systemic lupus erythematosus: a randomized, double-blind, placebo-controlled study.

Lupus·2016
Same author

Subunit vaccine H56/CAF01 induces a population of circulating CD4 T cells that traffic into the Mycobacterium tuberculosis-infected lung.

Mucosal immunology·2016

Area of Science:

  • Immunology
  • Rheumatology
  • Pharmacology

Background:

  • Rheumatoid arthritis is a chronic autoimmune disease.
  • Leflunomide (Arava) is an immunosuppressive disease-modifying antirheumatic drug (DMARD).

Purpose of the Study:

  • To evaluate the efficacy and safety of leflunomide in rheumatoid arthritis treatment.
  • To review data from pivotal randomized clinical trials and post-marketing experience.

Main Methods:

  • Analysis of data from three pivotal randomized clinical trials.
  • Review of post-release clinical experience and safety data.

Main Results:

  • Leflunomide demonstrated efficacy in treating rheumatoid arthritis.
  • Safety profile evaluated through clinical trials and real-world data.

Conclusions:

  • Leflunomide is an approved and effective treatment option for rheumatoid arthritis.
  • Post-release data support the efficacy and safety of leflunomide in clinical practice.