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Parathyroid hormone-related protein in pancreatic exocrine cancer associated with hypercalcaemia
P Bandyopadhyay1, S Baksi, D Bandyopadhyay
1Department of Medicine and Surgery, St Mary's Hospital, Newport, Isle of Wight.
International Journal of Clinical Practice
|March 29, 2003
Abstract:
Hypercalcaemia is a common complication of malignancy seen in about 10% of cases of advanced cancer. Although hypercalcaemia is not uncommon with endocrine tumour of the pancreas, hypercalcaemia with cancer of the exocrine pancreas unrelated to bone metastasis has been rarely reported. We report a case of undifferentiated pancreatic cancer with severe hypercalcaemia due to parathyroid hormone-related protein produced by the tumour cells that did not respond to medical management.