Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neural growth hormone: an update.

Steve Harvey1, Kerry Hull

  • 1Department of Physiology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7. steve.harvey@ualberta.ca

Journal of Molecular Neuroscience : MN
|March 29, 2003
PubMed
Summary

Growth hormone (GH) is produced in the brain before the pituitary gland, suggesting it may function as a neuropeptide. This review explores neural GH regulation and its roles in health and disease.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Professional Development, Shifting Perspectives, and Instructional Change among Community College Anatomy and Physiology Instructors.

CBE life sciences education·2021
Same author

Some Believe, Not All Achieve: The Role of Active Learning Practices in Anxiety and Academic Self-Efficacy in First-Generation College Students.

Journal of microbiology & biology education·2020
Same author

Growth Hormone Neuroprotection Against Kainate Excitotoxicity in the Retina is Mediated by Notch/PTEN/Akt Signaling.

Investigative ophthalmology & visual science·2019
Same author

Regenerative Effect of Growth Hormone (GH) in the Retina after Kainic Acid Excitotoxic Damage.

International journal of molecular sciences·2019
Same author

Overcoming Carrier Concentration Limits in Polycrystalline CdTe Thin Films with In Situ Doping.

Scientific reports·2018
Same author

Growth Hormone: Therapeutic Possibilities-An Overview.

International journal of molecular sciences·2018

Area of Science:

  • Neuroendocrinology
  • Molecular Biology
  • Genetics

Background:

  • Growth hormone (GH) gene expression is detected in extrapituitary tissues, including the central and peripheral nervous systems.
  • Neural GH expression precedes its appearance in the pituitary gland during development.
  • Phylogenetic evidence suggests GH may have evolved as a neuropeptide.

Purpose of the Study:

  • To review recent studies on the regulation of neural GH.
  • To examine the roles of neural GH in both healthy and diseased states.
  • To highlight the significance of GH within the nervous system.

Main Methods:

  • Literature review of existing research on neural GH.
  • Analysis of studies investigating GH gene expression in neural tissues.
  • Synthesis of findings on GH's regulatory mechanisms and functional implications.

Main Results:

  • GH gene expression is confirmed in various brain regions and peripheral nerves.
  • Evidence supports a neuropeptide-like function for GH in the nervous system.
  • Neural GH plays critical roles in neurological health and disease pathogenesis.

Conclusions:

  • GH has significant extrapituitary functions, particularly within the nervous system.
  • Understanding neural GH regulation and function is crucial for neurological research.
  • Further investigation into neural GH is warranted for therapeutic applications.

Related Experiment Videos