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[Comparative study of two Tramadol prescription protocols for postoperative analgesia in children]
Olfa Kaabachi1, Hayet el Jaouani, Hathem Safi
1Service d'orthopédie infantile, Hôpital d'enfants de Tunis, Tunisie.
Insights
Tramadol effectively manages postoperative pain in children aged 1-6 years. Both intravenous and oral Tramadol provided satisfactory pain relief with manageable side effects like vomiting and mild sedation.
Area of Science:
- Pediatric Anesthesiology
- Pharmacology
- Pain Management
Background:
- Postoperative pain in children requires effective and safe analgesia.
- Tramadol is an opioid analgesic with potential utility in pediatric pain management.
Purpose of the Study:
- To evaluate the efficacy and safety of Tramadol for postoperative pain relief in children.
- To compare different dosing regimens of Tramadol in pediatric patients.
Main Methods:
- Prospective study involving 72 children aged 1-6 years.
- Two Tramadol regimens were used: intravenous (IV) followed by oral (PO) or a single IV dose.
- Pain, vital signs, and sedation were assessed every 3 hours using standardized scales (CHEOPS).
Main Results:
- Satisfactory analgesia was achieved in 70% of children with a 2 mg/kg IV dose and 60% with a 1 mg/kg IV dose.
- Analgesia duration was 24 hours in 62.5% of the IV/PO group and 80% of the oral Tramadol group.
- The primary side effects were vomiting (25%, higher with IV) and mild sedation (34%).
Conclusions:
- Tramadol demonstrates safety and efficacy as an analgesic in children.
- Both IV and oral Tramadol regimens can provide effective postoperative pain control.
- Further research may optimize Tramadol dosing for pediatric postoperative pain.
Abstract:
We reported the result of a prospective study concerning the use of Tramadol for postoperative analgesia in children. Seventy-two children 1 to 6 year's old were enrolled. Tramadol was given at a dose of 1 mg/kg for 30 minutes and Oral regimen started 4 hours after at a dose of 0.5 mg/kg/6 hours for 24 hours in 40 child. Only one dose of Tramadôl, 2 Mg/kg, was used in other 32 children. We assessed every 3 hours: pain scale (CHEOPS), respiratory rate, and cardiac rate, blood pressure and sedation scale. We obtained satisfactory analgesia in 70% of children since the first hour postoperatively with 2 mg/kg Tramadol and in 60% of them who received 1 mg/kg. In the first group, analgesia had lasted for 24 hours in 62.5% of children and in 80% of children with oral Tramadol. The main side effect was vomiting as reported in 25% of children especially after intravenous Tramadol and mild sedation in 34% of them. Tramadol is a safe and efficient analgesic molecule in children.