Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gene expression databases and data mining.

Pascale Anderle1, Manuel Duval, Sorin Draghici

  • 1ISREC, Lausanne, Switzerland.

Biotechniques
|April 1, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ozanimod Reduces Serum Neurofilament Light Chain (NfL) and Glial Fibrillary Acidic Protein (GFAP) and Modulates Innate and Adaptive Immunity in Patients with Low-to-Moderate Activity Relapsing-Remitting Multiple Sclerosis.

International journal of molecular sciences·2026
Same author

Real-world characterization of PD-L1 expression in patients with advanced esophagogastric adenocarcinoma in Spain.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2026
Same author

Prostate cancer in situ autovaccination with the intratumoral viral mimic poly-ICLC: Modulating the cold tumor microenvironment.

Med (New York, N.Y.)·2025
Same author

Prevalence of Salmonella spp. isolated from seagulls and pigeons in Barcelona, Spain and its genetic relatedness with Salmonella human clinical isolates.

Journal of infection and public health·2025
Same author

CytoAnalyst web platform facilitates comprehensive single cell RNA sequencing analysis.

Scientific reports·2025
Same author

A comprehensive review of spatial transcriptomics data alignment and integration.

Nucleic acids research·2025
Same journal

Investigating the interactomic landscape of survival motor neuron (SMN) and the SMNΔ7 truncated protein.

BioTechniques·2026
Same journal

Antigen retrieval-immunofluorescence on free floating sections to visualize the liver lobule and its cellular makeup.

BioTechniques·2026
Same journal

Special approach of droplet digital polymerase chain reaction (ddPCR) for transgene stability of a Chinese hamster ovary (CHO) cell line.

BioTechniques·2026
Same journal

Strand-specific quantification of L1 ORF0 and related transcripts by multiplex reverse transcription with tagged primers.

BioTechniques·2026
Same journal

Why and when should we choose digital PCR?

BioTechniques·2026
Same journal

Quantitative and unbiased lung alveolar septum assessment in an LPS experimental mouse model using 2D-spatial correlation image analysis from hematoxylin and eosin slides.

BioTechniques·2026
See all related articles

DNA microarray technology aids life science discoveries, but informatics challenges like data analysis and storage persist. This paper reviews essential databases and tools for microarray experiments, focusing on cancer research workflows.

Area of Science:

  • Life Sciences
  • Bioinformatics
  • Genomics

Background:

  • DNA microarray technology is a cornerstone in modern life science research, enabling significant discoveries.
  • Initial technical hurdles in microarray experiments are largely resolved, shifting focus to informatics challenges.
  • Effective management of expression and annotation data through databases is crucial for the research community.

Purpose of the Study:

  • To survey key databases and tools essential for DNA microarray experiments.
  • To present a generalized workflow for microarray experiments, illustrated with cancer research examples.
  • To evaluate the benefits and drawbacks of current microarray databases and propose improvements.

Main Methods:

  • Review of prominent databases serving as critical nodes in research networks.

Related Experiment Videos

  • Development of a generalized workflow scheme applicable to typical microarray experiments.
  • Application of the workflow to two specific cancer research case studies.
  • Analysis of existing array database functionalities, including their advantages and disadvantages.

    • Main Results:

    • Identification of essential databases and informatics tools supporting microarray data analysis and interpretation.
    • Demonstration of a standardized workflow for processing microarray data from experiment to interpretation.
    • Highlighting the critical role of integrated expression and annotation databases in knowledge repositories.
    • Discussion of limitations in current database systems and potential areas for enhancement.

    Conclusions:

    • The effective use of specialized databases and informatics tools is vital for overcoming challenges in DNA microarray data analysis.
    • A generalized workflow approach aids in navigating the complexities of microarray experiments and data management.
    • Improvements in current array databases are needed to better support the growing demands of life science research.