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[Pneumococcal vaccination in adults].

R E Jonkers1, W G Boersma

  • 1Academisch Medisch Centrum/Universiteit van Amsterdam, afd. Longziekten, Postbus 22.660, 1100 DD Amsterdam. r.e.jonkers@amc.uva.nl

Nederlands Tijdschrift Voor Geneeskunde
|April 2, 2003
PubMed
Summary

Pneumococcal vaccination protects against invasive infections, but adding it to influenza vaccines may not offer extra pneumonia protection for at-risk groups. Cost-effectiveness for widespread elderly use remains unclear.

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Cost-effectiveness analysis on elderly pneumococcal vaccination in the Netherlands: Challenging the Dutch Health Council's advice.

Vaccine·2019

Area of Science:

  • Infectious Diseases
  • Immunology
  • Public Health

Context:

  • Pneumococcal pneumonia and bacteremia are significant causes of illness and death, particularly in vulnerable populations.
  • Current vaccination strategies aim to reduce morbidity and mortality in high-risk groups.

Purpose:

  • To evaluate the additional protective benefits of pneumococcal polysaccharide vaccination when administered alongside influenza vaccination in at-risk populations.
  • To assess the cost-effectiveness of pneumococcal vaccination strategies in specific demographics, including the elderly and immunocompromised individuals.

Summary:

  • Available literature suggests no convincing evidence that adding pneumococcal polysaccharide vaccine to influenza vaccination provides additional protection against pneumococcal pneumonia in at-risk groups, including those over 65.
  • Pneumococcal vaccination is effective against invasive infections, and vaccinating all elderly individuals may be cost-effective.
  • Insufficient data exists on the added benefit of pneumococcal vaccination in individuals already receiving influenza vaccines, making a cost-effectiveness assessment for the Netherlands impossible.

Impact:

  • Highlights the need for further research into the synergistic effects of combined vaccinations.
  • Informs public health policy regarding optimal vaccination schedules for preventing pneumococcal disease.
  • Emphasizes the importance of considering individual immune response for vaccination efficacy in immunocompromised patients.

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