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Basiliximab interferes with the detection of soluble IL-2 receptor by the Immulite Immunoassay system
Michiel C Warlé1, Jaap Kwekkeboom, Hugo W Tilanus
1Department of Surgery, Erasmus Medical Center Rotterdam, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.
Journal of Immunological Methods
|April 2, 2003
Abstract:
The use of the Immulite Automated Immunoassay system is becoming an increasingly popular method for accurate and fast measurement of sIL-2R in serum. Here, we report that detection of sIL-2R using the Immulite Immunoassay system in serum samples of patients who are treated with basiliximab, a monoclonal antibody against the alpha-chain of the IL-2 receptor, may lead to false measurements.