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Updated: Sep 26, 2026

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Image-Guided Resection of Glioblastoma and Intracranial Implantation of Therapeutic Stem Cell-seeded Scaffolds
Published on: July 16, 2018
Central neural tumor destruction by controlled release of a synthetic glycoside dispersed in a biodegradable
Alfonso Fernández-Mayoralas1, Natalia De La Figuera, Mercedes Zurita
1Instituto de Química Orgánica General, CSIC, Juan de la Cierva 3, 28006 Madrid, Spain. iqofm68@iqog.csic.es
Journal of Medicinal Chemistry
|April 4, 2003
Abstract:
An octyl N-acetylglucosaminide derivative with a pentaerythritol chain at position 6 has been synthesized and evaluated as an inhibitor of neural tumor growth. The glycoside inhibited the growth of a neuroectodermic tumor implanted in rats and, when loaded on a slow-delivery polymer disk, caused the destruction of cultured human astroblastoma obtained after surgical biopsy.

