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Related Experiment Videos

Aggression in the elderly.

Henry Brodaty1, Lee-Fay Low

  • 1School of Psychiatry, University of New South Wales, Prince of Wales Hospital Sydney, Australia.

The Journal of Clinical Psychiatry
|April 4, 2003
PubMed
Summary

Aggression is a common symptom in dementia, linked to cognitive decline and environmental factors. Effective management requires assessing medical, psychological, and environmental variables, with pharmacotherapy showing proven efficacy.

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Area of Science:

  • Neuroscience
  • Gerontology
  • Behavioral Science

Background:

  • Aggression is a frequent behavioral symptom observed in individuals with dementia.
  • It is associated with frontotemporal dementia, increased dementia severity, cognitive decline, and other behavioral and psychological disturbances.
  • Environmental factors, neuropathological changes, and genetic polymorphisms influence aggression in dementia.

Purpose of the Study:

  • To review the associations and influencing factors of aggression in dementia.
  • To discuss the impact of aggression on patients, caregivers, and healthcare systems.
  • To outline evidence-based management strategies for aggression in dementia.

Main Methods:

  • Literature review of studies on aggression in dementia.
  • Analysis of factors contributing to aggression, including clinical and environmental variables.
  • Evaluation of treatment efficacy for pharmacotherapy and psychosocial interventions.

Main Results:

  • Aggression in dementia is linked to specific dementia types, severity, cognitive impairment, and psychological disturbances.
  • Aggression leads to increased psychotropic medication use, caregiver distress, and predicts institutionalization.
  • Pharmacotherapy has demonstrated efficacy, while psychosocial interventions show more limited evidence.

Conclusions:

  • Comprehensive assessment of medical, psychological, and environmental factors is crucial for managing aggression in dementia.
  • A multimodal approach integrating pharmacotherapy and psychosocial interventions may be beneficial.
  • Addressing aggression is vital to improve patient quality of life and reduce caregiver burden.

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