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Basal transcription factors
1Penn State University, Department of Biochemistry and Molecular Biology, 203 Althouse lab, University Park, Pennsylvania 16802, USA. Jcr8@psu.edu
Current Opinion in Genetics & Development
|April 4, 2003
Abstract:
The functions of the basal transcription factors involved in RNA polymerase II dependent transcription have been the focus of many years of biochemical analysis. Recent advances have shed some light on the structure of these factors, how conformational changes and intramolecular interactions regulate activity, and have revealed an expanded role for TFIIH in nuclear transcription.