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Pullulan is a slowly digested carbohydrate in humans.

Bryan W Wolf1, Keith A Garleb, Yong S Choe

  • 1Ross Products Division, Abbott Laboratories, Columbus, OH 43215, USA. bryan.wolf@abbott.com

The Journal of Nutrition
|April 4, 2003
PubMed
Summary
This summary is machine-generated.

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Pullulan, a fungal polysaccharide, significantly reduced blood glucose spikes compared to maltodextrin. However, it caused increased flatulence and breath hydrogen, indicating partial malabsorption in healthy adults.

Area of Science:

  • Nutrition Science
  • Gastroenterology
  • Metabolic Studies

Background:

  • Pullulan is an extracellular polysaccharide produced by Aureobasidium pullulans.
  • Understanding pullulan's metabolic and gastrointestinal effects is crucial for its dietary applications.

Purpose of the Study:

  • To evaluate the glycemic response to pullulan compared to maltodextrin.
  • To assess breath hydrogen production and gastrointestinal tolerance of pullulan.

Main Methods:

  • A randomized, double-masked, crossover study involving 28 healthy adults.
  • Subjects consumed 50g of carbohydrate from either maltodextrin or pullulan.
  • Blood glucose, breath hydrogen, and gastrointestinal symptoms were monitored postprandially.

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Main Results:

  • Pullulan significantly reduced peak blood glucose concentration and the overall glycemic area under the curve by 50% compared to maltodextrin.
  • Pullulan consumption led to increased breath hydrogen excretion for up to 8 hours postprandially.
  • Higher incidence and intensity of flatulence were reported after pullulan intake, suggesting malabsorption.

Conclusions:

  • Pullulan attenuates postprandial glycemic excursions more effectively than maltodextrin.
  • Pullulan is partially malabsorbed, leading to increased gas production and gastrointestinal discomfort.
  • Further research is needed to optimize pullulan's use in functional foods and supplements.