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Published on: October 4, 2019
Three new ingol diterpenes from Euphorbia nivulia: evaluation of cytotoxic activity
Veluri Ravikanth1, Vanimireddy Lakshmi Niranjan Reddy, Adelli Vijender Reddy
1Pharmacology Division, Indian Institute of Chemical Technology, Hyderabad-500 007, India.
Abstract:
The latex of Euphorbia nivulia afforded three new ingol diterpenes, 3-acetyl-8-methoxyl-7-angolyl-12-hydroxylingol (7), 3,12-diacetyl-7-hydroxy-8-methoxylingol (8), and 3,12-diacetyl-7-angolyl-8-hydroxylingol (9) along with five known ingol diterpenes 2-6 and a known triterpene cyclonivulinol (1). Their structures were established by means of spectroscopic analysis. Diterpenes 2-9 were evaluated for their cytotoxic activity.