Parathyroid hormone type I receptor expression in mammalian osteoclasts

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Parathyroid hormone's enhancement of bones' osteogenic response to loading is affected by ageing in a dose- and time-dependent manner.

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Parathyroid hormone type I receptor expression in mammalian osteoclasts

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Mechanical strain-mediated reduction in RANKL expression is associated with RUNX2 and BRD2.

Mechanical strain-mediated reduction in RANKL expression is associated with RUNX2 and BRD2.

Bone gain following loading is site-specifically enhanced by prior and concurrent disuse in aged male mice.

Parathyroid hormone's enhancement of bones' osteogenic response to loading is affected by ageing in a dose- and time-dependent manner.

Old age and the associated impairment of bones' adaptation to loading are associated with transcriptomic changes in cellular metabolism, cell-matrix interactions and the cell cycle.

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