Pulmonary ventilatory function in premenopausal women with and without genital descensus

A hypothesis on the existence of link between the changes in connective tissue in patients with genital descensus and impairments of their pulmonary function was made. In the sample of 40 patients, admitted to hospital for surgical correction of their genital descensus, their pulmonary ventilatory function was examined and compared with 40 matched female examinees without genital descensus. All the examinees were in premenopausis, nonsmokers and without history or clinical signs of the diseases that could affect their pulmonary function. Patients exhibited highly significant decrements in all expiratory flows, especially in the peak expiratory flow (-26%) and other flows at large lung volumes. The forced vital capacity and forced expired volume at 1 second were also decreased (-9% and -16%, respectively). The findings were typical for reduced strength of the expiratory muscles, suggesting the possible link between the lack of collagen and the impairments of pulmonary function in women with genital descensus.