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[Comparative study of neurophysiological effects of unsubstituted phenol ethers of alpha mono- and diglycerides]
Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales
|January 1, 1975
Abstract:
The addition of a second alpha-glyceryl to alpha-phenoxypropanediol strongly modifies the inhibitor actions on the synaptic transmission. These new di-ethers do not show solubility nor effect on the water superficial tension and simultaneously do not provoke any neurophysiological inhibitor effect. The ability of cellular penetration by lipidic solubility seems a necessary condition for pharmacological effect of alpha-glyceric ethers.