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Parasite infections in laboratory mice colonies
1Department of General Parasitology, Microbiological Institute, University of Wrocław, Przybyszewskiego 63, 51-148 Wrocław, Poland. annaok@microb.uni.wroc.pl
Polish Journal of Veterinary Sciences
|April 5, 2003
Summary
Common oxyurid parasites impact laboratory mice colonies. Infections are often more severe in male mice compared to females, influenced by host factors like age and strain.
Area of Science:
- Veterinary Parasitology
- Laboratory Animal Science
Background:
- Oxyurid parasites are common and problematic in laboratory mouse colonies.
- Understanding parasite life cycles, pathogenicity, and host immunity is crucial for colony health.
Purpose of the Study:
- To review common oxyurid parasite issues in laboratory mice.
- To examine the influence of host factors on infection severity.
Main Methods:
- Literature review of oxyurid parasites in laboratory mice.
- Analysis of host-parasite interactions, including age, sex, strain, and host status.
Main Results:
- Oxyurid life histories, pathogenicity, and immunity were examined.
- Host factors such as age, sex, strain, and status significantly influence infection.
- Helminth infections are generally more severe in male than in female vertebrate hosts.
Conclusions:
- Oxyurid infections pose a significant challenge to laboratory mouse colony management.
- Host characteristics play a critical role in determining infection outcomes.
- Sex is a key factor, with males exhibiting greater susceptibility to helminth infections.
