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Venous thromboembolism hospitalizations among American Indians and Alaska Natives

W Craig Hooper1, Robert C Holman, John A Heit

  • 1Hematologic Disease Branch, Division of AIDS, STD, and TB Laboratory Research, National Center for Infectious Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, GA 30333, USA. chooper@cdc.gov

Thrombosis Research
|April 5, 2003
PubMed

Insights

Venous thromboembolism (VTE) hospitalization rates in American Indian/Alaska Native (AI/AN) populations decreased from 1980-1996. Rates were higher for females and varied by region, but overall AI/AN VTE rates appear lower than Caucasian rates.

Area of Science:

  • Public Health
  • Epidemiology
  • Cardiovascular Health

Background:

  • Cardiovascular disease (CVD) is increasing in American Indian/Alaska Native (AI/AN) populations.
  • Venous thromboembolism (VTE) is a significant component of cardiovascular morbidity.

Purpose of the Study:

  • To describe VTE-associated hospitalizations among AI/AN patients.
  • To analyze trends and demographic variations in VTE hospitalizations within the AI/AN population from 1980-1996.

Main Methods:

  • Utilized the Indian Health Service (IHS) hospital discharge database.
  • Analyzed hospitalization rates, age at hospitalization, sex-specific rates, and regional variations.
  • Calculated rates per 100,000 population over the 17-year study period.

Main Results:

  • The average overall VTE hospitalization rate in AI/ANs was 33.1 per 100,000, showing a decrease from 38.4 (1980-1982) to 33.2 (1994-1996).
  • Female VTE hospitalization rates significantly decreased (46.1 to 36.7 per 100,000), while male rates remained unchanged.
  • VTE hospitalization rates were highest in the East (52.2) and lowest in Alaska (16.1 per 100,000).

Conclusions:

  • Overall VTE hospitalization rates in AI/AN populations have decreased and appear lower than in Caucasian populations.
  • Significant decrease in VTE hospitalizations observed in females, suggesting potential shifts in risk factors or healthcare access.
  • Regional disparities in VTE hospitalization rates highlight the need for geographically targeted public health interventions.

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