Novel Protease Inhibitors

Third RSC-SCI Symposium on Proteinase Inhibitor Design: Proteinase 2002, held May 13-14, 2002, in London, United Kingdom, drew an audience of about 140 scientists to the SCI's Belgrave Square headquarters to hear 17 speakers address various aspects of this theme. There was considerable emphasis placed upon the use of X-ray crystallography of enzyme-inhibitor complex as an integral tool in the design of improved protease inhibitors. This biennial meeting has established a reputation for being a key forum for the disclosure of new compounds, and this year's meeting was no exception, with much of the emphasis placed on novel inhibitors of either serine or cysteine proteases. (c) 2002 Prous Science. All rights reserved.